Without contrast media (question of a brain hemorrhage!): Demonstrated are round hypodense areas in the frontal lobes bilaterally.
2 days after initial CT scan. Bone window images (upper left) and 3-D reformations (lower right) demonstate the frontal sinuses: Evidence of a bony defect of the posterior wall of the right frontal sinus.
4 days after initial CT scan. T1-SE-weighted axial image after IV contrast administration: Depiction of two large fluid formations with rim enhancing walls in both anterior frontal lobes. Marked meningeal enhancement, especially frontal.
18 days after initial CT scan. T1-SE-weighted axial image after IV contrast administration: Depiction of two large fluid formations with rim enhancing walls in both anterior frontal lobes. Worsening of the surrounding edema (only shown here on T1). Persistent meningeal enhancement, especially frontally.
T1-SE weighted axial image after contrast media: 2 months after beginning therapy with antibiotics and hyperbaric oxygenation: The previously large frontal fluid formations on both sides are significantly reduced in size. Patient is asymptomatic.

Congenital frontal sinus defect complicated by multiple brain abscesses

By Roland Talanow


History: 10 year-old boy with changes in behaviour for 8 days noticed by parents. Since the day before hospital admission, the boy had a fever of 39,5 degrees Celsius. Admission to the hospital and CT performed with the concern for brain hemorrhage.


Findings:

CT 1: Without contrast media (question of a brain hemorrhage!): Demonstrated are round hypodense areas in the frontal lobes bilaterally. :: CT 1 ::
Without contrast media (question of a brain hemorrhage!): Demonstrated are round hypodense areas in the frontal lobes bilaterally.







CT 2: 2 days after initial CT scan. Bone window images (upper left) and 3-D reformations (lower right) demonstate the frontal sinuses: Evidence of a bony defect of the posterior wall of the right frontal sinus. :: CT 2 ::
2 days after initial CT scan. Bone window images (upper left) and 3-D reformations (lower right) demonstate the frontal sinuses: Evidence of a bony defect of the posterior wall of the right frontal sinus.







MRI 1: 4 days after initial CT scan. T1-SE-weighted axial image after IV contrast administration: Depiction of two large fluid formations with rim enhancing walls in both anterior frontal lobes. Marked meningeal enhancement, especially frontal. :: MRI 1 ::
4 days after initial CT scan. T1-SE-weighted axial image after IV contrast administration: Depiction of two large fluid formations with rim enhancing walls in both anterior frontal lobes. Marked meningeal enhancement, especially frontal.








MRI 2: 18 days after initial CT scan. T1-SE-weighted axial image after IV contrast administration: Depiction of two large fluid formations with rim enhancing walls in both anterior frontal lobes. Worsening of the surrounding edema (only shown here on T1). Persistent meningeal enhancement, especially frontally. :: MRI 2 ::
18 days after initial CT scan. T1-SE-weighted axial image after IV contrast administration: Depiction of two large fluid formations with rim enhancing walls in both anterior frontal lobes. Worsening of the surrounding edema (only shown here on T1). Persistent meningeal enhancement, especially frontally.







MRI 3: T1-SE weighted axial image after contrast media: 2 months after beginning therapy with antibiotics and hyperbaric oxygenation: The previously large frontal fluid formations on both sides are significantly reduced in size. Patient is asymptomatic. :: MRI 3 ::
T1-SE weighted axial image after contrast media: 2 months after beginning therapy with antibiotics and hyperbaric oxygenation: The previously large frontal fluid formations on both sides are significantly reduced in size. Patient is asymptomatic.









Discussion:
Congenital defects of the frontal sinus after sinusitis can lead to permeative inflammations of the meninges. An abscess development is therefore possible.



In this case, the subsequent therapy with antibiotics and hyperbaric oxygenation lead, to a continuous regression of the abcesses.
After further 3 months (images not shown), only inactive scar tissue are seen on the FLAIR-sequence.



Differential diagnosis: Multiple confluent brain metastases

Diagnosis confirmation: Laboratory diagnostics



Category: Pediatric

Region / Organ: Head-Brain and brain nerves

Etiology: inflammatory or infectious

References:
Roland Talanow, Wolfgang Hirsch. Congenital frontal sinus defect complicated by multiple brain abscesses. PedRad [serial online] vol 2, no. 12.
URL: www.PedRad.info/?search=20021227193320




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